21 Dec 2023 PROJECT PUBLICATION

Imptox scientists illuminate mycotoxin dangers: a comprehensive review on aflatoxin and fumonisin toxicity

 

In a recent publication, Imptox researchers contribute to a pivotal review in 'Toxins,' delving deep into the toxic effects of aflatoxin B1 and fumonisin B1, and their implications for food safety and human health.

In a world increasingly aware of environmental hazards, a recent publication stands out for shedding light on the invisible threats lurking in our food. The article, titled "Current Knowledge of Individual and Combined Toxicities of Aflatoxin B1 and Fumonisin B1 In Vitro," published in "Toxins" on November 13, 2023, marks a significant contribution by Imptox scientists Prof. Andreja Rajkovic and Mohamed F. Abdallah in understanding these perils. This comprehensive review, a collaborative effort by experts from Ghent University and Qilu University of Technology, delves into the world of mycotoxins - specifically aflatoxin B1 (AFB1) and fumonisin B1 (FB1).

These mycotoxins, predominantly found in staples like cereals, particularly maize, are not just contaminants; they are formidable adversaries to human health. The review meticulously analyzes their individual and combined toxic effects, primarily focusing on liver toxicity, a common aftermath of exposure to these toxins. The study reveals how AFB1 and FB1, when encountered together, can amplify their toxic impacts through synergistic interactions, highlighting a public health concern given the common co-occurrence of these mycotoxins in food products.

The critical findings of this review extend beyond the realm of mycotoxins. While the focus is on these fungal metabolites, the implications of this research resonate with the broader objectives of the Imptox project. It is important to note the potential for these mycotoxins to coexist with other environmental pollutants, such as micro- and nanoplastic particles (MNPs) who in turn may be carriers of other toxins, pathogens or contaminants. Although the current study doesn't explore this intersection, it subtly underscores the need for comprehensive research in understanding how mycotoxins might interact with MNPs in our food sources.

The publication serves as a reminder of the complex challenges we face in ensuring food safety and protecting public health. The work of Imptox scientists and their colleagues in this field is vital in our ongoing quest to understand and mitigate the risks posed by these invisible but impactful adversaries in our environment. As we continue to unravel the mysteries of how different contaminants interact and affect our health, the insights gained from such studies become increasingly essential in guiding policy decisions and shaping a healthier future.

 

Reference:

Chen X, F. Abdallah M, Chen X, Rajkovic A. Current Knowledge of Individual and Combined Toxicities of Aflatoxin B1 and Fumonisin B1 In Vitro. Toxins. 2023; 15(11):653.

https://doi.org/10.3390/toxins15110653